Turner syndrome mosaic fertility. May 21, 2025 · In this guide, we’ll break down what to know about mosaic syndrome and pregnancy, explore your fertility options and share how surrogacy can support your journey toward parenthood. Dec 5, 2023 · However, in a recent study by “The US National Institute of Health,” spontaneous pregnancies in women with a 45 XO karyotype, the classic form of Turner’s syndrome, were observed, suggesting that there are different alleles involved in the regulation of fertility, placed in different positions on the X chromosome (Table 1) (8). Aug 12, 2025 · In this post, we’ll review some of the information shared during the webinar “Fertility Preservation in Girls with Turner Syndrome” hosted by the Turner Syndrome Foundation, featuring guest speaker Dr. 7 % and 67. In the rare event of a pregnancy, it usually leads to maternal and fetal complications, including miscarriage. Oocyte cryopreservation after controlled ovarian hyperstimulation in mosaic Turner syndrome: another fertility preservation option in a dedicated UK clinic. a b s t r a c t In this article we review the existing fertility preservation options for women diagnosed with Turner syndrome and provide practical guidelines for the practitioner. IVF-OD = in vitro fertilization oocyte donation. Our aim is to evaluate reproductive and obstetric outcomes of natural conception and in-vitro fertilization (IVF) cycles in mosaic TS patients. Aug 1, 2022 · Turner syndrome (TS) is tightly associated with hypergonadotropic hypogonadism and ovarian dysgenesis, typically resulting in infertility in the great… Abstract Turner syndrome (TS) is an abnormality of the X chromosome affecting females. In this study, we report a case of mosaic Turner syndrome (45,X/46,XX) in Nov 9, 2019 · Figure 1 Parenting choices and fertility outcomes in Turner syndrome. Pregnancy is a high risk in women with TS; therefore, prepregnancy screening, counselling and co-morbidity optimisation are imperative. It is considered mosaic when an X chromosome is missing in some cells in people who have two X chromosomes. Aug 14, 2025 · While infertility is one of the primary symptoms of Turner Syndrome (TS), fertility treatments can help some patients, primarily those with mosaic TS. Women with Turner syndrome are at extremely high risk for primary ovarian insufficiency and El-Shawarby SA, Sharif AF, Conway G, Serhal P, Davies M. A total of 22 mosaic TS cases (seventeen 45,X/46,XX and five 45,X/46,XX/47,XXX karyotypes) were evaluated. Jan 28, 2024 · Turner syndrome is a chromosomal condition involving a person’s sex chromosomes. . Turner syndrome (TS) is characterized by a complete or partial absence of one X chromosome (1). Kutluk Oktay–an OB/GYN physician and professor at Yale University. Live birth and abortion rates were found as 32. The most frequent chromosome constitution is 45X0, although approximately half of patients have a mosaic chromosome complement, the most common being 45X0/46XX (15%) and 46XXq or 46XXp deletions (6%). 3 %, respectively in 52 pregnancies. This genetic defect causes infertility in most cases, but less commonly in patients with the mosaic form of Turner syndrome. There are several reproductive options available for women with Turner syndrome, including adoption or surrogacy, assisted reproductive techniques, and in rare cases spontaneous pregnancy. Turner syndrome is the most common sex chromosome abnormality in women, occurring in approximately 1 in 2500 live births. Nov 6, 2022 · Spontaneous pregnancy, occurring mainly in women with mosaic TS, is uncommon and most women with TS require fertility treatments. ccqt olcu bpura avyad ayaqh jvts aykk lpbkcu bgonem istkn